1. one who supplies potent liquor;
one who has an unsteady brain, as one intoxicated ...1598 obs.
2. potent liquor, a strong drink ...1639 obs.
from tickle + -brain
FIRST DOCUMENTED USE
1598 - see EXAMPLE below
"...Falstaff: Peace good pint-pot, peace good tickle-braine.
Harrie, I doe not onelie maruaile where thou spendest thy
time, but also how thou art accompanied...."
From: The History of Henrie the Fourth
- William Shakespeare